• Bisphosphonates are a well established standard of

  2019-05-04

  

  Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated

• Preference for injectable therapy over oral therapy contrary

  2019-05-04

  

  Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne

• Cerrone et al reported that the mechanism of CPVT

  2019-05-04

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• Detailed data were available in

  2019-05-04

  

  Detailed data were available in Kilifi not only on carriage of vaccine types of pneumococci, but also on receipt of vaccine by the individuals in the study, and the overall vaccine coverage in the vasopressin receptor was also known. The data suggest that vaccine coverage of around two-thirds of ch

• Transformation of sanitation related knowledge into routine

  2019-05-04

  

  Transformation of sanitation-related knowledge into routine practice is hindered by traditional mindsets and the absence of awareness and an attitude to learn. Poverty has been described as a barrier to following safe hygiene practices. Regular use of footwear is equally important for the prevention

• Volvemos nosotros a tomar el hilo

  2019-05-04

  

  Volvemos nosotros ion channels tomar el hilo. El proyecto en cuestión remonta a las de Michel chevalier, publicadas en París en 1836, y que ya circulaban en chile al menos desde 1842. Para la llegada de Bilbao a Francia en 1845, el libro de chevalier era todo un éxito editorial. Había alcanzado en

• No son para nada desde ables las producciones que abordan

  2019-05-04

  

  No son para nada desdeñables las producciones que abordan la reflexión ética y bioética desde una perspectiva moriniana. A diferencia de la reflexión ética clásica, la bioética se extiende amiodarone hcl un conjunto de temas más amplios y diversos, que en cierta forma recubre al conjunto de los camb

• Although the NCCN IPI is a promising simple scale based

  2019-05-04

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• Almost all the information we have on clinical

  2019-05-04

  

  Almost all the information we have on clinical epidemiology of patients with UMI-77 failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clear picture of clinical chara

• The primary tool in the pharmacological management of

  2019-05-04

  

  The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress

• It s April and the

  2019-04-30

  

  It\'s (April 25) and the theme is “End malaria for good”. If I\'m not mistaken, that means eradication. In one of the first Comment pieces ever published, asked “Is it possible? Is it worth it? Should we do it?” and the pppa is still divided. Despite remarkable progress in prevention via vacc

• Uno de los rasgos m s in

  2019-04-30

  

  Uno de los rasgos más interesantes que encontramos en este retrato (figura 1) es la madurez y prolijidad que Portinari Madecassoside en unos cabellos bien peinados —aunque con unas entradas muy pronunciadas y unas patillas perfectamente recortadas— en la piel marcada por el paso del tiempo, no obsta

• br Case report We report a case of

  2019-04-30

  

  Case report We report a case of an 18 year-old Caucasian male who was found to have thrombocytopenia at birth, with a platelet count of 58,000/mm3. Bone marrow biopsy was first performed in 1993, at 13 months of age, and showed 70–80% cellular marrow with occasional megakaryocytes and no evidenc

• Abstract Background Substantial progress has

  2019-04-30

  

  Abstract Background Substantial progress has been made in reducing the incidence and prevalence of malaria. In 2016, 111 countries have eliminated malaria and another 35 countries, are making progress toward elimination of the disease. However, little is known about how much governments and donors

• In addition the TAA treated groups show http

  2019-04-30

  

  In addition, the TAA-treated groups showed a significant reduction in body weight with significantly increased liver weights and sizes compared to control rats, but NJ cotreatment reversed those defects (Table 1). The reduction in body weights could be attributed to the toxic effect of TAA throughou

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