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In summary we confirm that HB F
2018-11-12
In summary, we confirm that HB1.F3.CD and HB1.F3.CD.IFN-β lxr agonist selectively migrated toward breast cancer cells. This is likely due to various chemokines expressed by the tumor cells and their cognate receptors expressed on the stem cells, such as SCF/c-kit and VEGF/VEGFR2, respectively. The v
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br Materials and methods br Results br Discussion
2018-11-12
Materials and methods Results Discussion Cellular therapeutics may function via either replacement of a lost cell population (e.g. generation of new dopamine neurons or myelinating oligodendrocytes), restoration of a cellular function (e.g. synthesis/secretion of an enzyme in the case of a
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All iPSC derived neurons demonstrated expression of function
2018-11-09
All iPSC-derived neurons demonstrated expression of functional neurotransmitter receptors, responding to glutamate/glycine, GABA and to a lower extend to acetylcholine. Interestingly, the neuronal cultures also developed synchronized spontaneous calcium oscillations, which were likely to reflect car
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Recently new genome modifying methods using sequence specifi
2018-11-09
Recently, new genome-modifying methods using sequence-specific endonucleases, such as zinc-finger nuclease (ZFN), transcription activator-like effector nuclease (TALEN), and clustered regularly interspaced short palindromic repeat (CRISPR)-associated protein 9 (CRISPR/Cas9) systems, were developed o
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br Experimental Procedures br Acknowledgments br Introductio
2018-11-09
Experimental Procedures Acknowledgments Introduction The human palatine tonsil is part of a circular collection of specialized B-lymphoid structures located in the oropharynx at the opening of the aerodigestive tract (Figure 1A). The outer surface of the human palatine tonsil is lined with
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br Introduction In mammalian testes spermatogonial stem cell
2018-11-09
Introduction In mammalian testes, spermatogonial stem cells (SSCs) are a rare subset of the undifferentiated spermatogonial population that is tasked with providing continuity to the spermatogenic lineage (Oatley and Brinster, 2008, 2012). In addition, SSCs possess regenerative capacity, and foll
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Kohonen s network training takes place in two stages First
2018-11-09
Kohonen\'s network training takes place in two stages [9]. First, the distances from the training samples to each CE (neuron) are calculated by the formula [12]: where is the weighting coefficient linking the input vector to the cluster MLN4924 j. The values are transmitted to the competitive
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Overall obesity can lead to renal functional disorders and i
2018-11-09
Overall, obesity can lead to renal functional disorders and induce hypertension through a variety of mechanisms: (Hall, 1997; Hall et al., 1999; Hall et al., 2002; Hall et al., 2010; Hall et al., 2015; Hall et al., 2014). Activation of sympathetic nervous system; Physical–mechanical compression; Ren
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nitric oxide synthase inhibitors Seldon has proposed that du
2018-11-09
Seldon has proposed that during human development, white matter grows outward and expands to the overlying cortex similar to a balloon, affecting the capacity of the cortex (Seldon, 2005). The different rates of expansion in particular nitric oxide synthase inhibitors regions create regional differ
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ginsenoside rh2 The ECIS technique can monitor
2018-11-09
The ECIS technique can monitor the viability of cell by measuring electric signals from the ginsenoside rh2 exposed to toxic substances [8–11]. The ECIS sensor uses alternating-current (AC) with a wide frequencies (from 100Hz to 64kHz) to measure the impedance of in vitro cells seeded on the sensor
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br Acknowledgments This work was supported by
2018-11-09
Acknowledgments This work was supported by SENTAN, Japan Science and Technology Agency (JST). Part of the microfluidic channel fabrication was conducted at the AIST Nano-Processing Facility, supported by the “Nanotechnology Platform Program” of the Ministry of Education, Culture, Sports, Science
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La profunda reacci n conservadora que hemos experimentado
2018-11-09
La profunda reacción conservadora que hemos experimentado en el plano de las ideas, de la que la degradación del debate sobre el desarrollo económico no es más que una expresión, no se explica, por tanto, por la supuesta fortaleza teórica de las ideas neoliberales hoy imperantes en el seno de la “ci
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br Determinaci n de la elasticidad
2018-11-09
4. Determinación de la elasticidad del gasto Para obtener la elasticidad del gasto en Salud de los hogares con y sin remesas se procedió order AV-951 realizar una regresión con factor de interacción (Cuadro 5), y cuyos parámetros resultaron significativos a un nivel de confianza del 95%. Como se
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melk inhibitor Resalta especialmente el cap tulo del
2018-11-09
Resalta especialmente el capítulo del ttp que restringe la asistencia no comercial a empresas del Estado, ya que afecta tanto a los países asociados como a los que no lo están; convirtiéndose en un arma de doble filo al representar un instrumento de contención para la expansión de las empresas estat
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Conflict of Interest br Extreme genetic variability is
2018-11-09
Conflict of Interest Extreme genetic variability is the hallmark of HIV‐1 infection and it represents a major challenge for antiviral treatment and vaccine development. HIV‐1 group M dominates the global pandemic. Nine subtypes, 68 circulating recombinant forms (CRF) and countless unique recombin
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