• AMG-517 In patients with systolic heart

  2019-05-05

  

  In patients with systolic heart failure and a wide QRS complex, cardiac resynchronisation therapy (CRT) using left ventricular (LV) pacing has been shown to enhance survival, reduce heart failure hospitalisation and enhance exercise capacity in patients with all AMG-517 of heart failure. The patien

• Paying now rather than forever

  2019-05-05

  

  Paying now rather than forever has never been as relevant as a global health solution to the HIV pandemic than in 2013. The relative success of the ongoing replenishment session for the Global Fund is a positive signal, although still insufficient considering the evidence-based targets that are set

• br Conflict of interest br

  2019-05-04

  

  Conflict of interest Introduction Patients with structural heart disease have an increased risk of sudden cardiac death, secondary to ventricular tachyarrhythmias in most cases. Implantable cardioverter–defibrillators (ICDs) are the treatment of choice. However, ventricular tachyarrhythmias ca

• rtks br Conflict of interest br Case presentation A

  2019-05-04

  

  Conflict of interest Case presentation A 64-year-old female presented to the emergency room with persistent dizziness that began early that morning. She had a 30-year history of palpitations and known electrocardiogram (ECG) abnormalities. Her pulse was irregular at 130–270min−1 and blood pre

• Complete resection of the tumor with negative margins at the

  2019-05-04

  

  Complete resection of the tumor with negative margins at the time of diagnosis appears the most preferred mode of intervention towards favorable prognosis. It is worth mentioning that the germline sodium channel blockers of DICER1 is believed as the genetic cause in the majority of PPB; consequentl

• Bisphosphonates are a well established standard of

  2019-05-04

  

  Bisphosphonates are a well-established, standard-of care treatment option to reduce the frequency and severity and time of onset of the skeletal related events (SREs) in patients with bone metastases due to either solid tumours or multiple myeloma [21–33]. From many years, BPs have been incorporated

• Preference for injectable therapy over oral therapy contrary

  2019-05-04

  

  Preference for injectable therapy over oral therapy [17], contrary to our findings from a previous study [18], could reflect the fact that most patients have not received an oral bone-targeted agent for metastatic disease. However, the practical advantages of an injectable therapy and the lack of ne

• Cerrone et al reported that the mechanism of CPVT

  2019-05-04

  

  Cerrone et al. reported that the mechanism of CPVT was due to delayed afterdepolarization‐induced triggered activity in a focal Purkinje network in a knock-in (RyR2) mouse [36]. In addition, chemical ablation of the RV endocardial cavity with Lugol׳s solution, which selectively destroys the Purkinje

• Detailed data were available in

  2019-05-04

  

  Detailed data were available in Kilifi not only on carriage of vaccine types of pneumococci, but also on receipt of vaccine by the individuals in the study, and the overall vaccine coverage in the vasopressin receptor was also known. The data suggest that vaccine coverage of around two-thirds of ch

• Transformation of sanitation related knowledge into routine

  2019-05-04

  

  Transformation of sanitation-related knowledge into routine practice is hindered by traditional mindsets and the absence of awareness and an attitude to learn. Poverty has been described as a barrier to following safe hygiene practices. Regular use of footwear is equally important for the prevention

• Volvemos nosotros a tomar el hilo

  2019-05-04

  

  Volvemos nosotros ion channels tomar el hilo. El proyecto en cuestión remonta a las de Michel chevalier, publicadas en París en 1836, y que ya circulaban en chile al menos desde 1842. Para la llegada de Bilbao a Francia en 1845, el libro de chevalier era todo un éxito editorial. Había alcanzado en

• No son para nada desde ables las producciones que abordan

  2019-05-04

  

  No son para nada desdeñables las producciones que abordan la reflexión ética y bioética desde una perspectiva moriniana. A diferencia de la reflexión ética clásica, la bioética se extiende amiodarone hcl un conjunto de temas más amplios y diversos, que en cierta forma recubre al conjunto de los camb

• Although the NCCN IPI is a promising simple scale based

  2019-05-04

  

  Although the NCCN-IPI is a promising simple scale based on conventional clinical factors, its usefulness remains controversial [6,7]. It should be evaluated in populations of different regions and ethnicities before adopting it for routine clinical use. Conflict of interest Report At presenta

• Almost all the information we have on clinical

  2019-05-04

  

  Almost all the information we have on clinical epidemiology of patients with UMI-77 failure is collected in North America or in western European countriesTherefore, the work of Hisham Dokainish and colleagues in this issue of , is very welcome. Their study provides a clear picture of clinical chara

• The primary tool in the pharmacological management of

  2019-05-04

  

  The primary tool in the pharmacological management of PTSD is the use of selective serotonin reuptake inhibitors [55,56], but positive response rates are generally limited. In addition, non-pharmacological treatment such as CBT has been shown to be effective for PTSD [57]. Psychological distress

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