• The hypothesis derived from the work of McNamara et al

  2020-07-28

  

  The hypothesis derived from the work of McNamara et al. [1] was that the portion of the glycine-rich region around Q23 may be essential for interaction with ATP and ADP, making it important in catalytic activity. The current data presented for the DAPKQ23V mutant support this hypothesis. A logical e

• fructose 1 6 bisphosphatase br Improved Synthetic Cytokines

  2020-07-28

  

  Improved Synthetic Cytokines Assemble Novel Receptor Complexes Recombinant forms of many cytokines are successful drugs, including human growth hormone (hGH), EPO, TPO, G-CSF, IFNs, IL-2, and IL-11 [2]. For all of the previous fructose 1 6 bisphosphatase of cytokine, conjugates, fusion proteins,

• br Conflict of interest br Acknowledgements

  2020-07-28

  

  Conflict of interest Acknowledgements This work is funded by the National Institutes of HealthR01-GM069909 (YMC), Welch Foundation (I-1532; YMC), Leukemia and Lymphoma Society Scholar award (YMC), CPRIT (RP120352; YMC) and the UT Southwestern Endowed Scholars Program (YMC). We thank Q. Sun and

• br Results and discussion br Conclusions The need for

  2020-07-28

  

  Results and discussion Conclusions The need for small-molecule probes and inhibitors of P4H is evident from the lack of structural information about this AR-13324 essential enzyme as well as the list of fibrotic diseases associated with collagen overproduction. The newly discovered role of P4

• Our results indicate that BoCk

  2020-07-28

  

  Our results indicate that BoCk1c, BoCk1d, and BoCk1e are paralogs that may have arisen via gene duplications following the separation of Brassica from Arabidopsis. We do not know whether these genes are on the same or different chromosomes, but probably they are not duplicated in tandem, considering

• Spearman s rank correlations between LDL cholesterol levels

  2020-07-28

  

  Spearman\'s rank correlations between LDL cholesterol levels and cholesterol po1 markers are reported in Table 4. Sitosterol and stigmasterol in hyperabsorber families had a positive correlation with LDL cholesterol. However, no correlation was found for cholesterol absorption markers in non-hyperab

• Introduction In vitro synthetic biology has received conside

  2020-07-27

  

  Introduction In vitro synthetic biology has received considerably less attention than in vivo processes so far (Foster and Church, 2007). However, cell-free biosynthetic production is very likely to become important for many biotechnological challenges for reasons such as (energy) efficiency, syste

• Prostate cancer bone metastases result in

  2020-07-27

  

  Prostate cancer bone metastases result in mixed, heterogeneous osteoblastic and osteolytic lesions. Osteoblastic lesions are characterized by excess deposition of new bone, whereas osteolytic lesions are characterized by the destruction of bone. These two types of PCa bone metastases all cause distu

• DDR and DDR are collagen

  2020-07-27

  

  DDR1 and DDR2 are collagen receptor tyrosine kinases: DDR1 is activated by fibrillar (mainly type I and V) and non-fibrillar (type IV) collagen, and DDR2 is exclusively activated by fibrillar collagen (Alves et al., 1995, Olaso et al., 2002, Valiathan et al., 2012). In normal tissues, DDR1 is expres

• br Introduction The notion of the

  2020-07-27

  

  Introduction The notion of the Wiskostatin and its regulatory restriction points was first proposed in the 1970s and early 1980s. The machinery components associated with this process were identified and characterized through many genetic and biochemical studies, mainly in yeast, but also in sea

• br Funding This study was

  2020-07-27

  

  Funding This study was financially supported by the Defence Research and Development Organization (DRDO), Ministry of Defence, India (DIP-263). The first author, Garima Chauhan, is the recipient of a fellowship from the University Grant Commission (UGC), India. G. Kumar and P. Kumari recieved fel

• Our dietary reconstruction relies primarily on collagen

  2020-07-27

  

  Our dietary reconstruction relies primarily on collagen data. Considering the impact of local environment on the stable isotope ratios of foodwebs (Herrscher and Le Bras-Goude, 2010; Drucker and Henry-Gambier, 2005; Kinaston et al., 2014), specific attention was paid to characterize the stable carbo

• RQ What are the different factors

  2020-07-27

  

  RQ2: What are the different factors that influence the decision to choose among different component origins? In total eleven factors grouped into three high-level themes that influence the decision to choose a component origin were identified. The project metrics factors are: time, cost, effort and

• An Accelerated Degradation Test ADT is the method used to

  2020-07-27

  

  An Accelerated Degradation Test (ADT) is the method used to analyze (2). ADT extends the QALT technique. Rather than looking at failure times, ADT uses degradation measures to produce a time to failure. ADT fits well for aging-related failures as these are particularly difficult to empirically obser

• Due to its several industrial applications the

  2020-07-27

  

  Due to its several industrial applications, the recombinant production of collagen and all its derivatives as gelatins has been pursued for many years in different biological systems as mammalian agenerase receptor (Toman et al., 1999), tobacco plants (Ruggiero et al., 2000), silkworms (Tomita et a

15510 records 761/1034 page Previous Next First page 上5页 761762763764765 下5页 Last page