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In general up to date no study has considered thermodynamic
2020-01-30
In general, up to date, no study has considered thermodynamic modeling to estimate the ganciclovir of SO2 by different DESs. Since experimental measurements are time consuming and expensive, general and accurate theoretical models are vital to estimate SO2 solubilities in different DESs over wide ra
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HC-030031 Conventional configurations for alkanolamine and a
2020-01-30
Conventional configurations for alkanolamine and HC-030031 gas are not suitable to represent the chemical reaction between acid gas and alkanolamines. Nevertheless, Dowell et al. [17] have successfully represented the phase behaviour of CO2-water-MEA systems by using SAFT-VR [18] without any consid
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br Results and discussion br Conclusion br
2020-01-30
Results and discussion Conclusion Experimental section Pharmacological studies Introduction Survival analysis is a set of statistical methods that aim at modeling the relationship between a set of predictor variables and an outcome variable and, in particular, prediction of the time w
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From materials science it is
2020-01-30
From materials science, it is known that the differences in the annealing temperature is the main factor that mostly influences La (Takai et al., 2003, Cançado et al., 2006). In analogy, controlling the pyrolysis temperature and Lubiprostone synthesis during residues burning might be a key aspect to
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It is also meaningful to
2020-01-30
It is also meaningful to discuss whether VSOR Cl− channel-induced apoptosis is correlated with the ER pathway. Thus, in this study, we sought to clarify the intrinsic relationship between VSOR Cl− channels and the level of ER stress-related proteins. The research results are as follows: the expressi
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To develop antagonists selective for the mouse EP receptor
2020-01-29
To develop antagonists selective for the mouse EP1 receptor, we started with compound (), synthesized as previously described (). Diethyl dipicolinic tlr inhibitor () was reduced with NaBH to . Parikh–Doering oxidation of with sulfur trioxide–pyridine complex and DMSO produced the unstable aldehy
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The ubiquitin proteasome system Ub P
2020-01-29
The ubiquitin–proteasome system (Ub–P) is the main cellular machinery for protein turnover in eukaryotic cells (Glickman and Ciechanover, 2002). Degradation by Ub–P involves two steps. Target proteins are selectively, specifically, and covalently attached to ubiquitin (Ub) chains, followed by Ub-tag
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The intracellular redox situation of MC T E cells
2020-01-29
The intracellular redox situation of MC3T3-E1 RN486 after exposure with fluoride has been investigated and results revealed that the generation of ROS increased at a concentration-dependent manner, which indicated that NaF induced oxidative stress damage in MC3T3-E1 cells. Fluoride-mediated induceme
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The androgen receptor AR is a steroid
2020-01-29
The androgen receptor (AR) is a steroid hormone receptor that plays a crucial role in the normal development of male reproductive tissues, and its high expression and/or relaxation of its regulation are strongly implicated in prostate cancer (PCa) [11]. Androgen binding induces conformational change
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br Acknowledgments The authors thank Elisabete Lepera
2020-01-29
Acknowledgments The authors thank Elisabete Lepera and Rosana Silva for technical support. The study was supported by FAPESP, CNPq and PADC/FCF-UNESP. T.T. Miguel was the recipient of a FAPESP (Proc. 05/05171-1) and R.L. Nunes-de-Souza of a CNPq (Proc. 303580/2009-7) fellowship. Introduction
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In summary our findings indicate that bFGF stimulates CPT ex
2020-01-29
In summary, our findings indicate that bFGF stimulates CPT1 expression, FA oxidation and lactate production with the participation of PPARβ/δ activation. On the other hand, this investigation shows that FSH concomitantly regulates the expression of genes involved in FA metabolism and in mitochondria
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To determine the time course of ZD P CPG DNA
2020-01-29
To determine the time course of ZD2767P+CPG2 DNA–DNA interstrand cross-link formation, HT29 and LS174T colorectal tumour 8220 synthesis were exposed to the drug for 10, 30 or 60 min. The levels of DNA interstrand cross-links in HT29 or LS174T cells did not increase with exposure time, suggesting th
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This work is inspired by the systematic work of Coutinho
2020-01-29
This work is inspired by the systematic work of Coutinho and co-workers, who obtained several very useful experimental data, which will be also used in our work, and applied the CPA equation of state for the modeling of systems relevant to the production of biodiesel [8], [9], [10], [11], [12], [13]
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Introduction The COMT gene is located
2020-01-29
Introduction The COMT gene is located on chromosomal band 22q11.2, extends over 28 kb, contains six exons, and encodes for catechol-O-methyl-transferase (Weinshilboum and Raymond, 1977; Grossman et al., 1992; Lundström et al., 1995; Bearden et al., 2005). This enzyme plays a major role in regulatio
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These findings further extend our knowledge of
2020-01-29
These findings further extend our knowledge of how P4 and/or E2 can mediate anxiety and fear responses. Female rats in behavioral estrous and ovx rats administered systemic P4 and/or E2 demonstrated significantly less anxiety in the open field and/or elevated plus maze, compared to diestrous rats, a
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