• br Conflict of interest br Introduction The use of implantab

  2019-04-25

  

  Conflict of interest Introduction The use of implantable defibrillation devices such as an implantable cardioverter–defibrillator (ICD) or a cardiac resynchronization therapy device with a defibrillator (CRT-D) is the primary therapy for improving prognoses of patients with life-threatening ve

• Heart failure is a complex disease

  2019-04-25

  

  Heart failure is a complex disease and the status of each patient is highly heterogeneous; therefore, nominal manufacturer-delivered device settings may not be optimal for all patients who receive CRT implantation. A growing body of evidence suggests hemodynamic and clinical status benefits associat

• In addition we evaluated the

  2019-04-25

  

  In addition, we evaluated the left atrium–left ventricle contraction sequence caused by the interatrial conduction delay. When we performed AV sequential pacing using the nominal AV delay setting, left atrial contractions were significantly delayed and were almost simultaneous with the left ventricu

• In several Western reports from large

  2019-04-25

  

  In several Western reports from large-scale comparative studies and epidemiological surveys, there was no significant difference in the incidence of thromboembolism between paroxysmal and persistent AF patients [46,47]. Data from our institution suggested that the incidence of cardiogenic thromboemb

• IL IL is another potential inhibitor of OBL

  2019-04-25

  

  IL-7: IL-7 is another potential inhibitor of OBL differentiation in MM that induces RANKL production by T lymphocytes [113] and mediates MM-induced OBL inhibition by down-regulating RUNX2 transcriptional activity [93]. IL-7 levels are increased in the marrow of MM patients and that IL-7 inhibited bo

• br Introduction Bone marrow adipocytes are one of the most

  2019-04-25

  

  Introduction Bone marrow adipocytes are one of the most abundant cell types found in bone marrow tissue. They constitute approximately 15% of the bone marrow volume in young adults, rising to 60% by the age of 65 years old [1]. Previously considered as inert space filling cells with little biolog

• Long marginalised as a disorder

  2019-04-25

  

  Long marginalised as a disorder confined to specific racial groups, sickle-cell disease is now assuming its rightful place as a major global public health problem. Most patients in the Americas, the Caribbean, and much of Europe have been of one racial group, which led to the common misconception th

• Introduction Atrial fibrillation AF is the

  2019-04-24

  

  Introduction Atrial fibrillation (AF) is the most common arrhythmia in adults and the most common cause of embolic stroke. AF affects approximately 0.8 million patients in Japan alone, and its incidence is expected to grow exponentially [1–3]. However, the electrophysiological mechanisms of the ini

• According to several cases earlier

  2019-04-24

  

  According to several cases earlier reported by Gandhi et al, the median time of acute pancreatitis occurring is 12 days (range: 9–16 days), from the last administration of BV, and most events occurred in the first course of BV treatment. One patient experienced recurrent pancreatitis in the fifth co

• Validation study findings showed that knowledge KR

  2019-04-24

  

  Validation study findings showed that knowledge (KR20=0.58) had moderate internal consistency. Even though this was fairly acceptable, the knowledge domain was considered a good test as KR20 tends to result in more conservative estimates than Cronbach’s alpha [28]. Enhancing the reliability of a que

• A type saddle back type or type

  2019-04-24

  

  A type 2 (“saddle-back type”) or type 3 ST-segment elevation cannot substitute for a type 1, unless converted to type 1 with fever or sodium drug challenge. A drug challenge–induced type 1 can be used to diagnose BrS only if accompanied by 1 of the criteria specified above. Type 2 is characterized b

• In the current study we first isolated primary

  2019-04-24

  

  In the current study, we first isolated primary HSCs from rat liver and then treated the cholecystokinin receptor with alcohol. As shown in Fig. 1, the mRNA levels of PCBP2 and type I collagen were increased significantly. In addition, the type I collagen mRNA level was more significantly increased

• br Although much attention centres on Afghanistan

  2019-04-24

  

  Although much attention centres on Afghanistan\'s political and security transitions, malnutrition is a foremost concern. Because an absence of adequate nutrition has crucial long-term effects on individuals and on social and economic development, nutrition rates in Afghanistan deserve attention a

• Al ser verdad lo anterior

  2019-04-24

  

  Al ser verdad lo anterior, no lo es menos que la cultura asentada en tiempos coloniales, a diferencia de la que llegó en los primeros tiempos de la conquista, respondía a la relativa ignorancia del mundo clásico en España, sobre todo del griego. Fue el país donde más se leyeron sus autores en traduc

• In recent years the impact that

  2019-04-23

  

  In recent years, the impact that food production and consumption have had on the environment has received increasing international attention. Some food production practices and consumption behaviours are putting the environment under a great stress, contributing to climate change. The food sector ac

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